Dawson's Smalls

A small team of just four, working with small penicillium fungoid growths helpers, all to heal some small patients, working class SBE youths, the very "4Fs of the 4Fs".

Dr Henry Dawson seemed to have kept his team deliberately small, not just to maximize his freedom from the people and institutions who wanted to financially shut him down, but also to make a point of the continuing abilities of small science and small science teams to still do major work.

Again, he deliberately chose to rub the fur of Allied medical science the wrong way when he decided to break a worldwide medical taboo, and after only all five weeks into his project, inject the raw penicillin made from the dismissed-as-too-primitive penicillium mold into his patients' blood stream.

This, rather than wait years or decades for Big Pharma and Big Medicine to painstakingly and slowly bring mass clinically tested synthetic penicillin to market.

Finally of course, Dawson seemed to doom his 'penicillin project' to years of failure by picking by far the hardest disease on the books to try and cure with the limited amounts he could make or obtain.

But of course his project was never about penicillin and he deliberately picked the SBEs because they were 'the least of these' on everyone else's medical priority list, if a shooting war broke out.

Dawson's small team picked the small penicillium mold and the small SBEs out of the dustbin of history, where they had been both dismissively tossed, and then made out of them something truly wondrous and globe-changing to behold....

How a handful of Gotham unfits rescued the unbroken bronco of modern medicine (un-patentable natural lifesaving penicillin-for-all) and set it free to do good

When your life hangs in the balance because of bacterial infection and all else has failed, hospitals reach for Plan G - a needleful of Penicillin G - 87 years old and still our most potent , safest and yet by far the cheapest lifesaver.

Big Pharma practically giving away its most potent and yet safest lifesaver - that hardly sounds like the Big Pharma you and I know --- and hate !

Penicillin still remains un-patentable - still remains made naturally by tiny bugs in a bottle , not by human chemists in a factory.

It still finds its main use as an internal lifesaver not as an external antiseptic for cuts and scrapes.

And it still is a widely available lifesaver - regardless of skin color or lack of income .

Partly because it is cheap because it is un-patentable so no one firm or nation can control its production  but mostly because making it available for all is a longstanding tradition since the last year of WWII.

But if Alexander Fleming , that Presbyterian-raised Scot from Old Scotland had had his will, none of this good news would have happened.

Thankfully, another Presbyterian-raised Scot , but this time from New Scotland (Henry Dawson), was there to thwart his will ...

Tortoise and Hare : the race between indies and suits for wartime penicillin

Indie Pen

The Tortoise was 'indie' penicillin , New York City penicillin , Emma Lazarus penicillin - humanized and naturalized. It had none of the innings for nine tenths of the game but pulled way ahead at the end.

The Hare was 'suits' penicillin : weaponized , synthesized , eugenicized , profitably-patentable, 'I am a Republican in a Democratic administration and I am here to help you 'penicillin.

It was supported by  the Anglo-American scientific-medical establishment ,  by Big Pharma and by the British Conservative-dominated government and some all-powerful agencies of the wartime American government.

Big Pharma -Kos : sacrificing WWII's bumpy SBE patients as scapegoats to restore a streamlined conscience

Pharmakos were those unfortunates in Ancient Greece who happened to be poor and crippled and without any local, prosperous, relatives to succour them, who were thus forced into slavery, begging or petty criminality.

When a crisis arose and the normally smoothly streamlined social sphere developed strains and cracks, the Pharmakos were scapegoated restored it.

Social 'bumps' (the Pharmakos) were beaten out - metaphorically as well as in actuality - to return streamlining and normalcy.

This was done by a sacred solemn ritual of executing, expelling or beating a physically, mentally or culturally deformed (misfitting) individual , preferably one without any powerful relatives close by to exact possible vengeance.

I have always wondered why the wartime American NAS felt it was so very very important to strenuously deny penicillin to the very small number of SBE patients asking for it between the summer of 1942 and the summer of 1943.

They were the only patients denied lifesaving penicillin for a condition where penicillin was not just a cure but the only cure.

(I have absolutely no qualms about denying penicillin (limited or not) to dying patients against which penicillin had no possible effect - viral diseases for one.)

One of the biggest social strains a war produces on the home front is the inequality of individual and family sacrifice - who goes to war and gets shot - who stays home and gets promoted ever upwards into the slots of those away fighting overseas.

I believe that the upwardly mobile chicken hawks on the NAS Death Panels turning down these SBE requests (and thus sentencing innocents to a quasi-judicial death) may have unconsciously felt they were thus 'dealing death' just like those of their age group who had been or were in combat zones - salving in a complex way their own internal social strain and bumpiness.

Who can tell ...?

"Unfit valour" : They defied Allied & Axis eugenics (and their own physical failings) to bring us "Penicillin-for-All"

What would penicillin look like today if Hitler, Stalin or Churchill had delivered it - instead of Dawson ?

In 1943 , Hitler, Stalin or Anglo-American Big Pharma could have delivered penicillin to us - delivered us penicillin either as expensive as Avastin or only to be given to the truly deserving Proletarian or Aryan.

But against the eugenic-mad world of 1943 , perhaps only a bunch of misfits and unfits could have delivered us inexpensive, abundant ,un-patented, un-encumbered Penicillin-for-All...

World's most effective lifesaver is also the most beloved AND the cheapest

That's not at all like Big Pharma, the world's least beloved industry.

Usually their effective lifesavers cost a big fortune and their ineffective ones merely cost a small fortune.

By contrast, our beloved inexpensive penicillin G has seen wide use among the world's poorest patients and as a result  billions of us have had a 'free ride' :  a quasi-herd immunity to millennium old contagious bacterial infections like Rheumatic Fever.

Diseases today most of us under the age of 50 have never even heard of and most doctors have never seen.

But it almost didn't happen ; we almost lost inexpensive- penicillin-for-all

At the height of WWII, when the only other anti-bacterial agent, the Sulfa drugs, were visibly failing, Big Pharma in Britain and America held off mass production of the only alternative (Penicillin) until they had synthesized it and patented it.

Meanwhile , in the middle of that desperate world war, American and British diplomats sat down to leisurely haggle over how to divide the massive world profits on synthetic penicillin ; visions of post-war sugar plums dancing through their heads.

Now you don't have to be a student of foreign affairs to suspect that America is very, very, very reluctant to sign international treaties --- so this alone suggests how profitable the two superpowers thought patented penicillin would be.

That could only mean sticker shock at the drugstore cash register for ordinary families, of course.

And the world's poor ? Forget it !

One doctor bucked the combined Anglo-American scientific-medical establishment ,and eventually when even Doctor Moms joined in,  the American politicos smelling electoral disaster backed off.

The British politicians did not and the election shock of 1945 was the price they paid.

The story of the smallest Manhattan Project and its battle for inexpensive-penicillin-for-all is fascinating  ---- and almost totally unknown even to penicillin historians....

Lifesaving 'too cheap to meter:' the legacy of the smallest Manhattan Project

Remember that solemn pledge from the biggest Manhattan Project ?

After killing a few hundred thousand civilians overseas, they promised to make up for it by offering us endless, abundant, safe electricity at prices 'too cheap to meter'.

They were joking, right ?!

By contrast, consider the legacy of the smallest Manhattan Project.

It has offered us decades of lifesaving at prices 'too cheap to meter'.

That is an amazing feat considering it was performed against the combined resistance from the biggest of the wartime Allied  governments and from many politically powerful firms in wartime's Big Pharma.

Penicillin, more than 85 years after its initial discovery, still can stop cold the toughest bacterial infections going, and do so at prices dirt cheap, offering us true life saving at prices too cheap to meter.

Contrast that to today's to cancer drugs,  averaging at costs between $100,000 to $350,000 a year, that can only promise to extent the average life by about four months.

This is because natural penicillin was born in the public domain, born the original genetic drug , and Man failed totally to synthesize it and expensively patent it.

Penicillin is often called the miracle drug and perhaps its biggest miracle was economic, not medical : it could be given the opportunity to save hundreds of millions worldwide because it wasn't priced like Avastin but rather was almost as cheap as water.

(A real miracle - and I repeat, it almost didn't happen, we almost lost inexpensive penicillin.)

That was because our busy wartime Allied bureaucrats and busy wartime drug executives spent zillions in scarce tax dollars to try to synthesize and patent penicillin rather than getting down to doing Job One with readily available natural penicillin.

Their Job One and Two and Three should have been saving lives in a worldwide war crisis.

Henry Dawson's 'Penicillin-for-all' did not just mean making it available to all at a steep price, like Avastin : it meant making it available to all patients, at a price even the poorest can afford...

"Irish Jimmy" Duhig and his Uisce Beatha : Penicillin as Orange Juice

I woke up the middle of last night to find I had a bad cold and so naturally got to thinking about its prevention and cure.

Its natural and unnatural cure and what all this had to do with the unknown history of wartime's crude penicillin.

Naturally, one avoids respiratory colds and worse by eating lots of fresh fruits and vegetables , drinking lots of liquids, getting plenty of rest, and living a secure existence in a well ventilated sizeable home.

One gets more and deadlier respiratory diseases living stressed lives in cramped, il-ventilated homes without adequate fresh fruit and vegetables.

The other way to avoid colds and such is to daily pop a lot of synthetic vitamin pills for your entire life.

You will then have become that most sought after client of Big Pharma : someone from (A) a sizeable group of people who have a (B) 'chronic' 'disease' and (C)  who can afford to buy the moderately expensive solution to the disease, daily, from a drug company for the rest of their lives.

Insulin for middle class diabetics was a big money spinner for Big Pharma , starting in the 1920s, for just those reasons ---- just as the mania for vitamin pills for the middle class was in the 1930s.

No mind that the middle class were hardly needing any vitamins, based on their adequate and varied diets based on the more expensive fresh products of Nature.

They may not have needed any tiny white synthetic vitamin pills .

But they did have enough money to buy them and they did have the necessary ingrained faith in "Science" that helped them swallow Big Pharma's claims regarding the need for daily synthetic vitamin supplements to succeed in this "busy, complex, Modern Age."

Now adequate Vitamin C is regarded as vital to prevent and limit colds.

We can get enough simply eating enough fresh vegetables but most  of us like to supplement this with a tasty morning glass of golden orange juice rather than dash down a tasteless dry little white pill of 100% pure synthetic Vitamin C.

Horrors ! said 1930s Big Pharma and its tame pill-pushing scientific "consultants".

That glass of orange juice or the even more basic orange or lime itself is so impure - containing merely a tiny fraction of one percent pure Vitamin C.

Who knows what bad toxins lurk within it ?

Well we now agree that the orange or lime holds only other goodnesses - like soluble and insoluble fibre.

Scientists knew this even back in the 1930s, but the majority had tagged along on a culture-wide Modernist mania for purity - racial and chemical - and couldn't see the fibre benefits for all their dark fears of possible unknown impurities in the innocent orange.

Nasty Reds lurking under "only innocent-looking" orange beds or groves.

Jimmy Duhig, along with Henry Dawson, Robert Pulvertaft and a very few others didn't buy all this : they thought that the golden solution of crude penicillin was the literal Water of Life, Aqua Vitae or Uisce Beatha , for their dying patients.

Even after 100% pure natural penicillin was available after the war, Dawson's co-worker Gladys Hobby, now a key employee of Big Pharma, was allowed to publish a scientific article seeking to demonstrate that crude penicillin was ,in some way, more effective than the pure stuff !

But back to our trios of modern-day James Linds.

Instead of waiting - perhaps centuries - for a patently-profitable synthetic penicillin pill , they did a James Lind and starting saving lives - right now ! - with the penicillium equivalent of Lind's natural lime juice for scurvied sailors : natural crude penicillium juice.

The fact that these still-unknowns saved many lives while the now-famous Howard Florey merely fiddled about trying fruitlessly to make synthetic penicillin merely reminds of the power of Big Pharma and their many scientific sycophants on Nobel Prize committees.....

I propose to a (book) editor.... in an elevator

Clutching my manuscript to my heaving chest (insert bodice here) I got down on one knee and said to her , "This Manhattan Project is from Venus ---- and so are most of your customers."

"So enough already on any more books about Manhattan Projects that kill. This wartime Manhattan P. saved lives : its all about life and love and the whole nine months."

"Listen to your mother, she says you won't even be here if it wasn't for penicillin : cheap, abundant, natural, non-patented penicillin."

"Now does that sound like how Big Pharma normally operates ?

Yeah, exactly --- this time, despite America being at war, Doctor Mom was in charge and she saw to it that it was done up right."

"If this book proposal has legs - and I think it does , try to think of those legs as being shapely, shaved and belong to an avid reader of character-driven narratives ."

"Besides, market-wise, isn't it long overdue for a Good News Story to come out of WWII's Bad News War ?"

"Give it a read and then get back to me before the bidding war gets heavy -----  'cause, baby, this here book project is all about peace, love and understanding...."