The website for New York City's Columbia-Cornell medical centre is finally touting the two famous universities' involvement in the triumph of wartime's natural penicillin.
So of course, the collective minds at C-C Medical choose to emphasize the project that quietly failed at their institute, not the one that succeeded beyond all measure.
For what they are really marking is wartime Cornell's failure to produce synthetic penicillin at commercial prices and in commercial grade purity.
Oh yes, they did produce incredibly small amounts of real penicillin but the yield was so tiny one might almost think it was an unexpected impurity in another process altogether.
Which in a sense it was : in chemical terms their synthesis did indeed produce a molecule, but it was not the beta lactam molecule fragment that gives penicillin and all subsequent beta lactams (still 75 years on, our major antibiotics) their ability to destroy bacteria without harming humans.
A very mixed result then for this attempt at fulfilling prewar modernity's dream of synthetic autarky.
What Columbia-Cornell has not yet honoured and will never yet honour (not until we can proclaim for sure that modernity is fully dead and buried) is that at Columbia, a small team led by Martin Henry Dawson worked in commensality with the tiny penicillium spores to create the world's first natural penicillin pilot plant.
And that on October 16th 1940, they gave the very first needlefuls of penicillin-the-antibiotic to a black lad and a Jewish lad dying from then invariably fatal SBE.
Eventually their penicillin cured SBE and prevented the disease that caused it : Rheumatic heart Disease : the leading killer of school age minority, poor and immigrant kids until the 1960s.
(Clearly not a triumph any rich donor-seeking medical centre wants to tout, obviously.)
Further : that this then led a small soda pop supplier in Brooklyn to make most of the war's penicillin by natural means - the means we still use to start the production of all the beta lactams that still dominate the world we call antibiotics.
In fact, very first signal triumph for what was to become today's huge and postmodern microbiology and microtechnology !
Shameful really...
Wednesday, February 25, 2015
At Columbia-Cornell Medicial, pre-war modernity ain't dead yet
Labels:
columbia cornell medical,
martin henry dawson,
microtechnology,
modernity,
natural penicillin,
october 16th 1940,
pfizer,
postmodernity,
synthetic penicillin,
vincent du vigneaud
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Why My Urgency ?
- Michael Marshall
- Nova Scotia
- Histories of WWII all start with the presumption that it was a war raged between humans and human ideologies, with Nature’s climate and geography as side issues easily surmounted.My blog, on the contrary will only accept that it was conflict between humans and their ideology that STARTED the war but that it was the barriers thrown up by Mother Nature (geography & climate) that turned it into a war that lasted between 6 to 15 years and expanded to thoroughly involve all the world’s oceans and continents. High Modernity may have started the war convinced that Nature had been conquered and was about to be soon replaced by human Synthetic Autarky and that only human Tiger tanks and human Typhoon planes were to be feared. But by the end, more and more people had lost their naive faith in Scientism and were beginning to accept that humanity was thoroughly entangled with both the Nature of plants, animals & microbes as well as the Nature of so called “lesser” humanity. By 1965, the world was definitely entering the Age of Entanglement. Billions still believed - at least in part -with the promises of High Modernity but intellectually & emotionally, it was no longer dominant...
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